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Anoushka Joglekar
Keeping with the idea that creativity and necessity are at the heart of scientific progress, I am excited about developing new tools that can help uncover information that lies just beyond our collective reach.
Academic Appointments
Postdoctoral Research Associate
G2 Lab, New York Genome Center
New York, NY
Current - 2023
- Developing methods to study the 3D genome architecture
Education
PhD, Computational Biology
Tilgner Lab, Weill Cornell Medicine
New York, NY
Current - 2017
- Thesis: A cell-type centric view of alternative splicing in the mammalian brain
B.S., Mathematics
The Ohio State University
Columbus, OH
2017 - 2013
B.A. English
The Ohio State University
Columbus, OH
2017 - 2013
- Thesis: From the atom to the grain of sand: Ascending the Stoppardian ladder
Research Experience
Graduate Student Researcher
Tilgner Laboratory
Weill Cornell Medicine
Current - 2018
Undergraduate Researcher
Coombes Laboratory
The Ohio State University
2017 - 2016
- Developed the Newman algorithm for outlier detection in small samples and applied to TCGA cancer data
Undergraduate Researcher
Terman Laboratory
The Ohio State University
2016 - 2014
- Worked on 2 dimensional network of neuron-astrocyte gap junctions to model cerebral ischemic stroke
Teaching Experience
Mentoring rotation students
N/A
Weill Cornell Medicine
2021 - 2018
- Devised rotation projects and mentored MS students through their thesis, and PhD students throughout the course of their 10-15 weeks-long rotation
College Algebra
Department of Mathematics
The Ohio State University
2017 - 2016
- Served as a teaching assistant to supplement college algebra lectures, where I conducted recitation sections twiice a week
Calculus I, II, III
Mathematics and Statistics Learning Center
The Ohio State University
2016 - 2015
- Mathematics tutor for undergraduates
Selected Publications
The variables on RNA molecules: concert or cacophony? Answers in long-read sequencing
Nature Methods
N/A
2022
- Authored with Careen Food, Julien Jarroux, Hagen TIlgner
- Link to article
Accurate isoform discovery with IsoQuant using long reads
Nature Biotechnology
N/A
2022
- Authored with Andrey Prjibelski, Alla Mikheenko, Hagen Tilgner
- Link to article
Sequencing of individual barcoded cDNAs using Pacific Biosciences and Oxford Nanopore Technologies reveals platform-specific error patterns
Genome Research
N/A
2022
- Authored with Mikheenko A, Prjibelski AD, Hagen Tilgner
- Link to article
ScisorWiz: Visualizing Differential Isoform Expression in Single-Cell Long-Read Data
Bioinformatics
N/A
2022
- Authored with Alexander Stein, Hagen Tilgner
- Link to article
A spatially resolved brain region- and cell type-specific isoform atlas of the postnatal mouse brain
Nature Communications
N/A
2020
- Authored with Prjibelski AD, Mikheenko A, Hagen Tilgner
- Link to article
Getting the entire message: Progress in isoform sequencing
Frontiers in Genetics
N/A
2019
- Authored with Simon Hardwick, Adam Frankish, Paul Flicek, Hagen Tilgner
- Link to article
SynGO: an evidence-based, expert-curated knowledge base for the synapse
Neuron
N/A
2019
- Authored with Frank Koopmans, Hagen Tilgner, Guus Smit et al.
- Link to article
Single-cell isoform RNA sequencing characterizes isoforms in thousands of cerebellar cells
Nature Biotechnology
N/A
2018
- Authored with Ishaan Gupta, Paul Collier, Ahmed Mahfouz, Hagen Tilgner et al.
- Link to article
Neuroprotective role of gap junctions in a neuron astrocyte network model
Biophysical journal
N/A
2016
- Authored with Richard Buckalew, Sarah Wong, Gemma Huguet, David Terman et al.
- Link to article
Presentations and invited talks
A spatiotemporal view of alternative splicing in the mouse brain
Speaker
Nanopore Community Meeting
2022
Single-nuclei isoform sequencing unlocks barcoded exon connectivity in frozen tissu
Speaker
DNA After Hours - hosted by Agilent
2022
A cell-type centric view of isoform expression reveals combination patterns of transcript elements across spatiotem-
poral axes of the brain
Speaker
ISMB - RNA COSI
2022
A spatially resolved brain region and cell type-specific isoform atlas of the postnatal mouse brain
Invited talk
Tri-I CBM Recruitment, Weill Cornell Medicine
2021
A spatially resolved brain region and cell type-specific isoform atlas of the postnatal mouse brain
Invited talk
PacBio SMRT Journal Club
2021
Building towards a brain region and cell type-specific isoform atlas of the postnatal mouse brain
Invited talk
ACCESS Research Seminar
2021
A computational framework for quantifying alternative splicing at a single cell resolution
Invited talk
Instituto de Medicina Molecular, University of Lisbon
2021
Ask the experts: Single cell Iso-Seq
Panelist
PacBio Virtual User Meeting
2021
Neuronal cell-type heterogeneity through the lens of alternative splicing
Bedside to Bench seminar series
Feil Family Brain and Mind Research Institute, Weill Cornell Medicine
2020
Neuronal cell-type heterogeneity through the lens of alternative splicing
Invited talk
Tri-I CBM Recruitment, Weill Cornell Medicine
2020
Neuronal cell-type heterogeneity through the lens of alternative splicing
Oral presentation
10X Genomics
2020
Cell-type signatures of brain-region specific splicing in postnatal development
Poster presentation
Biological Data Science, CSHL
2020
Single cell Iso-Seq
Oral presentation
PacBio Summit
2020
Enhanced interpretation of ScISOr-Seq reveals distinct programs of alternative splicing in the developing mouse brain
Lightning talk
Genome Informatics, CSHL
2019
Variety is the splice of life
Three Minute Thesis Competition
Weill Cornell Medicine
2019
Leadership
Admissions Committee
N/A
Computational Biology Summer Program, MSK
2022 - 2020
Tri-I Biotech Club
Director of Internal Affairs
Weill Cornell Medicine
2022 - 2020
Tri-I CBM Leadership
Social Media Liason
New York, NY
2021 - 2020
Skype a Scientist
Scientist
New York, NY
2020 - 2018
NIH Graduate School Career Fair
Representative - Tri I CBM
N/A
2020
Tri-I CBM Leadership
Research in progress liaison
New York, NY
2019 - 2018
Vincent DuVigneaud Memorial Research Symposium
Publicity Committee
Weill Cornell Medicine
2019
Annual Biomedical Research Conference for Minority Students (ABRCMS)
Representative - Tri I CBM
Anaheim, CA
2019
Tri-I CBM Leadership
Social Chair
New York, NY
2018 - 2017
Awards and Honors
Weill Cornell Graduate Fellowship
N/A
N/A
2022
JTech CSHL Biological Data Science 2020 Scholarship
N/A
N/A
2020
- The JXTX Foundation provides support for students to attend conferences in computational biology and data science, where they can present their work and form connections with other researchers in the field
David O Frantz thesis award
N/A
N/A
2018
- Recognizes the most outstanding thesis completed by an English major during the previous three semesters.
Social Justice and Anti-Racism Taskforce
N/A
Weill Cornell Medicine
2022 - 2020